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Mayo Clinic
Heart disease
Overview
Heart disease describes a range of conditions that affect the heart. Heart disease includes:

Blood vessel disease, such as coronary artery disease.
Irregular heartbeats, called arrhythmias.
Heart conditions that you're born with, called congenital heart defects.
Disease of the heart muscle.
Heart valve disease.
Many forms of heart disease can be prevented or treated with healthy lifestyle choices.

Symptoms
Heart disease symptoms depend on the type of heart disease.

Symptoms of heart disease in the blood vessels
Coronary artery disease is a common heart condition that affects the major blood vessels that supply the heart muscle. A buildup of fats, cholesterol and other substances in and on the artery walls usually causes coronary artery disease. This buildup is called plaque. The buildup of plaque in the arteries is called atherosclerosis (ath-ur-o-skluh-ROE-sis). Atherosclerosis reduces blood flow to the heart and other parts of the body. It can lead to a heart attack, chest pain or a stroke.

Symptoms of coronary artery disease can include:

Chest pain, chest tightness, chest pressure and chest discomfort, called angina.
Shortness of breath.
Pain in the neck, jaw, throat, upper belly or back.
Pain, numbness, weakness or coldness in the legs or arms if the blood vessels in those body areas are narrowed.
You might not be diagnosed with coronary artery disease until you have a heart attack, angina, a stroke or heart failure. It's important to watch for heart symptoms. Talk with your healthcare team about any concerns. Heart disease can sometimes be found early with regular health checkups.

Heart disease symptoms caused by irregular heartbeats, called arrhythmias
The heart may beat too quickly, too slowly or irregularly. Heart arrhythmia symptoms can include:

Chest pain or discomfort.
Dizziness.
Fainting or almost fainting.
Fluttering in the chest.
Lightheadedness.
Racing heartbeat.
Shortness of breath.
Slow heartbeat.
Heart disease symptoms caused by congenital heart defects
A congenital heart defect is a heart condition present at birth. Serious congenital heart defects usually are noticed soon after birth. Congenital heart defect symptoms in children could include:

Blue or gray skin. Depending on skin color, these changes may be easier or harder to see.
Swelling in the legs, belly area or areas around the eyes.
In an infant, shortness of breath during feedings, leading to poor weight gain.
Some congenital heart defects may not be found until later in childhood or during adulthood. Symptoms may include:

Getting very short of breath during exercise or activity.
Easily tiring during exercise or activity.
Swelling of the hands, ankles or feet.
Heart disease symptoms caused by diseased heart muscle, called cardiomyopathy
In the beginning, cardiomyopathy may not cause noticeable symptoms. As the condition gets worse, symptoms may include:

Dizziness, lightheadedness and fainting.
Fatigue.
Feeling short of breath during activity or at rest.
Feeling short of breath at night when trying to sleep, or waking up short of breath.
Rapid, pounding or fluttering heartbeats.
Swollen legs, ankles or feet.
Heart disease symptoms caused by heart valve disease
The heart has four valves. The valves open and close to move blood through the heart. Many things can damage the heart valves. If a heart valve is narrowed, it's called stenosis. If a heart valve lets blood flow backward, it's called regurgitation.

Symptoms of heart valve disease depend on which valve isn't working right. Symptoms may include:

Chest pain.
Fainting or almost fainting.
Fatigue.
Irregular heartbeats.
Shortness of breath.
Swollen feet or ankles.
When to see a doctor
Get emergency medical help if you have these heart disease symptoms:

Chest pain.
Shortness of breath.
Fainting.
Always call 911 or your local emergency number if you think you might be having a heart attack.

If you think you may have symptoms of heart disease, make an appointment for a health checkup.

Heart disease is easier to treat when found early.

Causes
Heart disease causes depend on the specific type of heart disease. There are many different types of heart disease.

How the heart works
To understand the causes of heart disease, it may help to understand how the heart works.

The heart has four chambers. The two upper chambers are called the atria. The two lower chambers are called the ventricles.
The right side of the heart moves blood to the lungs through blood vessels called the pulmonary arteries.
In the lungs, blood gets oxygen. The oxygen-rich blood goes to the left side of the heart through the pulmonary veins.
The left side of the heart then pumps the blood through the body's main artery, called the aorta. The blood then goes to the rest of the body.
Heart valves
Four valves in the heart keep blood flowing in the right direction. These valves are:

Aortic valve.
Mitral valve.
Pulmonary valve.
Tricuspid valve.
Each valve has flaps, called leaflets or cusps. The flaps open and close once during each heartbeat. If a valve flap doesn't open or close properly, less blood moves out of the heart to the rest of the body.

Heartbeats
The heart's electrical system keeps the heart beating. The heart's electrical signals start in a group of cells at the top of the heart called the sinus node. They pass through a pathway between the upper and lower heart chambers called the atrioventricular (AV) node. The movement of the signals causes the heart to squeeze and pump blood.

Causes of coronary artery disease
A buildup of fatty substances in the arteries, called atherosclerosis, is the most common cause of coronary artery disease. Risk factors include an unhealthy diet, lack of exercise, obesity, and smoking. Healthy-lifestyle choices can help lower the risk of atherosclerosis.

Causes of irregular heartbeats, called arrhythmias
Common causes of arrhythmias or conditions that can lead to them include:

Heart muscle disease, called cardiomyopathy.
Coronary artery disease.
Diabetes.
Illegal drugs such as cocaine.
Emotional stress.
Too much alcohol or caffeine.
Heart conditions present at birth, called congenital heart defects.
High blood pressure.
Smoking.
Heart valve disease.
Some medicines, herbs and supplements.
Causes of congenital heart defects
A congenital heart defect happens while a baby is growing in the womb. Healthcare professionals aren't sure exactly what causes most congenital heart defects. But gene changes, some medical conditions, some medicines, and environmental or lifestyle factors may play a role.

Causes of heart muscle disease, called cardiomyopathy
The cause of cardiomyopathy depends on the type. There are three types:

Dilated cardiomyopathy. This is the most common type of cardiomyopathy. The cause is often unknown. It may be passed down through families, which means it's inherited.
Hypertrophic cardiomyopathy. This type is usually passed down through families.
Restrictive cardiomyopathy. This type of cardiomyopathy can happen for no known reason. Sometimes a buildup of protein called amyloid causes it. Other causes include connective tissue disorders.
Causes of heart valve disease
Many things can cause a damaged or diseased heart valve. Some people are born with heart valve disease. If this happens, it's called congenital heart valve disease.

Other causes of heart valve disease can include:

Rheumatic fever.
Infection in the lining of the heart valves, called infectious endocarditis.
Connective tissue disorders.
Risk factors
Risk factors for heart disease include:

Age. Growing older increases the risk of damaged and narrowed arteries and a weakened or thickened heart muscle.
Sex assigned at birth. Men are generally at greater risk of heart disease. The risk in women increases after menopause.
Family history. A family history of heart disease increases the risk of coronary artery disease, especially if a parent developed it at an early age. That means before age 55 for a male relative, such as a brother or your father, and 65 for a female relative, such as your mother or a sister.
Smoking. If you smoke, quit. Substances in tobacco smoke damage the arteries. Heart attacks are more common in people who smoke than in people who don't smoke. Talk with a healthcare professional if you need help quitting.
Unhealthy diet. Diets high in fat, salt, sugar and cholesterol have been linked to heart disease.
High blood pressure. High blood pressure that's not controlled can cause the arteries to become hard and thick. These changes alter blood flow to the heart and body.
High cholesterol. Having high cholesterol increases the risk of atherosclerosis. Atherosclerosis has been linked to heart attack and stroke.
Diabetes. Diabetes increases the risk of heart disease. Obesity and high blood pressure increase the risk of diabetes and heart disease.
Obesity. Excess weight typically worsens other heart disease risk factors.
Lack of exercise. Being inactive is associated with many forms of heart disease and some of its risk factors too.
Stress. Emotional stress may damage the arteries and make other heart disease risk factors worse.
Poor dental health. Having unhealthy teeth and gums makes it easier for germs to get into the bloodstream and travel to the heart. This can cause an infection called endocarditis. Brush and floss your teeth often. Also get regular dental checkups.
Complications
Possible complications of heart disease are:

Heart failure. This is one of the most common complications of heart disease. The heart can't pump enough blood to meet the body's needs.
Heart attack. A heart attack can happen if a piece of plaque in an artery or a blood clot moves to the heart.

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